Chemical Properties
T-Boc-Cystamine is a cleavable ADC linker that can be used to synthesize antibody-drug conjugates (ADCs).
Uses
Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
IC 50
Disulfide Cleavable Linker; Cleavable Linker
References
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:
10.1038/nrd.2016.268
