1-Palmitoyl-2-lauroyl-sn-glycero-3-PC

Appearance

1-Palmitoyl-2-lauroyl-sn-glycero-3-PC is a crystalline solid.

Uses

1-Palmitoyl-2-lauroyl-sn-glycero-3-PC is a carboxylate derivative and can be used as an intermediate in organic synthesis.

Description

1-Palmitoyl-2-lauroyl-sn-glycero-3-PC (1,2-PLPC) is a phospholipid containing palmitoyl (16:0) and lauryl (12:0) acyl substituents at the sn-1 and sn-2 positions, respectively. This mixed-chain phosphatidylcholine has been used to study chain-chain contact interactions that contribute to the structural stability of lipid membrane bilayers.¹

Definition

ChEBI: 1-palmitoyl-2-lauroyl-sn-glycero-3-phosphocholine is a phosphatidylcholine 28:0 in which the two acyl substituents at positions 1 and 2 are specified as palmitoyl and lauroyl respectively. It is a phosphatidylcholine 28:0 and a dodecanoate ester. It is functionally related to a hexadecanoic acid.

References

1. Li, S., Wang, Z.Q., Lin, H.N., et al. Energy-minimized structures and packing states of a homologous series of mixed-chain phosphatidylcholines: A molecular mechanics study on the diglyceride moieties Biophys. J. 65(4),1415-1428(1993).