Sodium 1,1-difluoroethylsulfinate

Uses

DFES-Na provides a direct approach to fluorinated heteroarylether bioisosteres by appending a 1,1-difluoroethyl group operationally simple and robust protocol. This reagent was developed by the Baran Group and is one of several reagents for the direct alkylation of heterocycles.

Learn More at the Professor and Product Portal of Professor Phil S. Baran.
Baran Diversinates(TM) Lead Diversification and Metabolism Prediction Flyer

reaction suitability

reaction type: C-C Bond Formation
reaction type: Fluorinations
reagent type: catalyst
reaction type: C-H Activation
reagent type: diversification reagent