1',4-Bis(t-butyl)-1,2-bis(diphenylphosphino)-3'-(di-i-propylphosphino)ferrocene, 98% HiersoPHOS-1

Reaction

1. Direct Arylation of Heteroaromatics with Congested, Functionalised Aryl Bromides at Low Palladium Loading (0.05-0.5 mol%): furans, thiophenes, thiazoles, pyrroles functionalized with alkyl, nitrile, aldehyde, keto, and ester groups coupling with ortho-and di-ortho-substituted aryl bromides (phenyl, naphtyl, anthracenyl) bearing alkyl, aryl, alcohol, nitrile, carbonitrile, and ethoxy groups.
2. Etherification of Functionalized Phenols with Chloroheteroarenes at Low Palladium Loading (0.2-0.5 mol%): para-, metaand ortho- mono and di-substituted phenols (bearing methyl, isopropyl, methoxy, fluoro, amino, and ester groups) coupling with chloro-pyridines, -quinolines, -hydroxypyridines, -pyrimidines, -thiazoles bearing electron-withdrawing or - donating cyano and methoxy groups.