Description
A tetracyclic alkaloid present in Leontice Eversmanii Bge. this base is laevorotatory with [α]
D - 7S.2°. It gives crystallines salts, e.g. the perchlorate, m.p.
252°C; methiodide, m.p. 297°C and the picrate as yellow needles, m.p.
177-9°C. The structure has been determined from the NMR and mass spectra.
The optically inactive form has been synthesized and has m.p. S5-7° C, giving a
crystalline hydrochloride, m.p. 215-7° C.
References
Platonova, Kuzovkov, Massagetov., 1. Gen. Chern. USSR, 23,880 (1953)
Rulko, Proskurnina., ibid, 31, 308 (1961)
Synthesis:
Mandell et ai., 1. A mer. Chern. Soc., 87, 5234 (1965)
