Uses
For use in histochemical staining of b-galactosidase actifvity.
General Description
The Senescence Cells Histochemical Staining Kit contains all the reagents required for identifying senescent cells using an assay based on a histochemical stain for b-galactosidase activity at pH 6. b-galactosidase activity is detectable in senescent cells, but not in quiescent, immortal, or tumor cells.
Biochem/physiol Actions
Replicative senescence is a growth-arrest state associated with loss of division potential, changes in cell morphology, shape and physical appearance, and the pattern of gene expression in cells.
