Ceftezole sodium

Uses

Ceftezole Sodiumis a salt form Ceftezole(C244315) which is a β-lactam, cephem antibiotic. It also exhibits potent α-glucosidase inhibitory activity and antidiabetic effect in streptozotocin-induced mouse.

Definition

ChEBI: Ceftezole Sodium is a N-acyl-amino acid.

Biological Activity

Ceftezole is a first generation cephalosporin with antibacterial activity. Ceftezole binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity causing bacterial cell lysis.