Chemical Properties
CLEAR COLOURLESS LIQUID
Uses
Solvent, intermediate.
Production Methods
2-Methyl-1-pentanol is prepared by the aldol condensation of
propionaldehyde and subsequent hydrogenation of the intermediate
2-methyl-2-pentanol. Commercially, the methyl-
1-pentanols are rarely used alone but as amixture.
Synthesis Reference(s)
Journal of the American Chemical Society, 77, p. 6052, 1955
DOI: 10.1021/ja01627a077
General Description
Nonaqueous lipase-catalyzed kinetic resolution of
racemic 2-methyl-1-pentanol in a continuously operated fixed bed reactor has been reported. Molar excess enthalpies of binary mixtures of 2-methyl-1-pentanol with
n-hexane and its isomers has been measured in a flow microcalorimeter.
Hazard
Moderate fire risk.
Safety Profile
Moderately toxic by
ingestion and skin contact. A skin and
severe eye irritant. Human systemic irritant
by inhalation. A flammable liquid; can react
with oxidizing materials. To fight fire, use
Con, dry chemical. When heated to
decomposition it emits smoke and acrid
fumes.
Purification Methods
Dry the 1-pentanol with Na2SO4 and distil it. [Beilstein 1 IV 1713.]
