Description
Corynecin I is a chloramphenicol-like antibiotic originally isolated from
Corynebacterium. It is active against Gram-positive and Gram-negative bacteria with MIC values of 5.2-83 μg/ml for
S. sonnei,
P. vulgaris,
K. pneumoniae, and
S. aureus among others.
Uses
Corynecin I is a chloramphenicol-like acyl nitrophenylpropylamine.
Uses
Corynecin I is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin I is active against Gram positive and Gram negative bacteria. Although less potent than chloramphenicol, corynecin I shows a similar species selectivity.
