Description
N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5.
Chemical Properties
White to Off-White Solid
Uses
N-Desethyl Vardenafil is a metabolite of Vardenafil, a phosphodiesterase 5 inhibitor.
References
[1] HEI-YOUNG KU. The contributions of cytochromes P450 3A4 and 3A5 to the metabolism of the phosphodiesterase type 5 inhibitors sildenafil, udenafil, and vardenafil.[J]. Drug Metabolism and Disposition, 2008, 36 6: 986-990. DOI:
10.1124/dmd.107.020099