(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine

Chemical Properties

Uses

Uses

Reactions

1. Chiral ligand for the asymmetric hydrogenation of β-keto esters.
2. Chiral ligand for enantioselective rhodium-catalyzed [2+2+2] carbocyclization reactions.
3. Chiral ligand for ruthenium catalyzed hydrogenation of (E)-β-(acylamino)acrylates to β-amino acids.
4. The Rhodium complex gives higher enantioselectivity for hydrogenation of (Z)-β-(acylamino)acrylates to β-amino acids.
5. Chiral ligand for copper-catalyzed asymmetric hydrosilylation of ketones.
6. Chiral ligand for asymmetric allylic substitution reactions using boronic acids as nucleophiles.
7. Gives useful selectivity in asymmetric Pauson-Khand-type cyclizations.