C16 Ganglioside GM2-d9 (d18:1/16:0-d9) (ammonium salt)

Description

C16 Ganglioside G_M2-d₉ (d18:1/16:0-d₉) is intended for use as an internal standard for the quantification of C16 ganglioside G_M2 by GC- or LC-MS. C16 Ganglioside G_M2 (d18:1/16:0) is a monosialated ganglioside.¹ It has been found in A2780 ovarian carcinoma cells, as well as purified ganglioside mixtures extracted from healthy postmortem and hemangioma-bearing human frontal lobe cortical tissue.^1,2 As this product is derived from a natural source, there may be variations in the sphingoid backbone.

Uses

C16 Ganglioside GM2-d9 (d18:1/16:0-d9) (C16 GM2-d9) ammonium saltis deuterium labeled C16 Ganglioside GM2 (d18:1/16:0) (ammonium salt)[1].

References

1. Schiopu, C., Flangea, C., Capitan, F., et al. Determination of ganglioside composition and structure in human brain hemangioma by chip-based nanoelectrospray ionization tandem mass spectrometry Anal. Bioanal. Chem. 395(8),2465-2477(2009).
2. Valsecchi, M., Aureli, M., Mauri, L., et al. Sphingolipidomics of A2780 human ovarian carcinoma cells treated with synthetic retinoids J. Lipid Res. 51(7),1832-1840(2010).