C24-PHYTOCERAMIDE
- Product NameC24-PHYTOCERAMIDE
- CAS34437-74-6
- CBNumberCB0788937
- MFC42H85NO4
- MW668.13
- MDL NumberMFCD08703058
- MOL File34437-74-6.mol
Chemical Properties
storage temp. | Store at -20°C |
solubility | Chloroform:Methanol (5:1): soluble |
form | A solid |
C24-PHYTOCERAMIDE Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
Cayman Chemical 22827 | 1mg | $44 | C24 Phytosphingosine (t18:0/24:0) ≥98% |
Buy |
Cayman Chemical 22827 | 5mg | $184 | C24 Phytosphingosine (t18:0/24:0) ≥98% |
Buy |
AK Scientific 7680CR | 1mg | $147 | N-Tetracosanoylphytosphingosine |
Buy |
C24-PHYTOCERAMIDE Chemical Properties,Usage,Production
Description
C24 Phytoceramide (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis.1,2,3 C24 Phytoceramide (t18:0/24:0) is composed of a phytosphingosine backbone amine-linked to a C24 fatty acid chain. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro.4,5 In a stratum corneum model of healthy skin, the incorporation of long-chain-containing phytoceramides, such as C24 phytoceramide (t18:0/24:0), increases permeability of the membrane in comparison with incorporation of dihydroceramides.6Definition
ChEBI: N-tetracosanoylphytosphingosine is a phytoceramide compound having a tetracosanoyl group attached to the nitrogen atom. It has a role as a Saccharomyces cerevisiae metabolite. It is a N-(very-long-chain fatty acyl)-sphingoid base and a N-acylphytosphingosine.References
1. Crossman, M.W., and Hirschberg, C.B. Biosynthesis of phytosphingosine by the rat J. Biol. Chem. 252(16),5815-5819(1977).2. Omae, F., Miyazaki, M., Enomoto, A., et al. DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine Biochem J. 379(Pt. 3),687-695(2004).
3. Mizutani, Y., Kihara, A., and Igarashi, Y. Identification of the human sphingolipid C4-
4. de Jager, M., Groenink, W., van der Spek, J., et al. Preparation and characterization of a stratum corneum substitute for in vitro percutaneous penetration studies Biochim. Biophys. Acta 1758(5),636-644(2006).
5. Basse, L.H., Groen, D., and Bouwstra, J.A. Permeability and lipid organization of a novel psoriasis stratum corneum substitute Int. J. Pharm. 457(1),275-282(2013).
6. ?kolová, B., Ková?ik, A., Tesa?, O., et al. Phytosphingosine, sphingosine and dihydrosphingosine ceramides in model skin lipid membranes: Permeability and biophysics Biochim. Biophys. Acta 1859(5),824-834(2017).
Preparation Products And Raw materials
Raw materials
C24-PHYTOCERAMIDE Suppliers
Global(17)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 | |
+1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 | |
0717-6449896 13886658719 |
root@zhongyitai.com | China | 1976 | 58 | |
1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 | |
400-9205774 | sales@glpbio.cn | China | 6870 | 58 | |
18818260767 | sales@chemegen.com | China | 11289 | 58 | |
18768175414 | gaojun@univ-bio.com | China | 24998 | 58 | |
027-59626688 18771149750 |
sales@amyjet.com | China | 3004 | 58 | |
029-63373950 15353716720 |
1052@dideu.com | China | 10004 | 58 | |
021-65675885 18964387627 |
customer_service@efebio.com | China | 8740 | 58 |
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