Description
Amphetamines are chemical compounds characterized by an α-
methylphenethylamine base structure. D-
amphetamine is a stimulant that binds the norepinephrine and dopamine transporters (EC
50s = 7.1 and 24.8 nM, respectively). 2-
Amino-
1-
phenylbutane is an amphetamine characterized by having an ethyl group in the alpha position. It has emerged as a potential recreational drug. This product is a mixture of the D and L isomers. The D isomer of this compound partially substitutes for D-
amphetamine in an animal discrimination analysis, suggesting that it weakly mimicks the signaling and stimulant properties of D-
amphetamine. This product is intended for forensic and research applications.
Uses
1-Phenyl-2-butanamine Hydrochloride is a derivative of Amphetamine (A634248); a CNS stimulant and anorexic.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 31, p. 824, 1988
DOI: 10.1021/jm00399a024
References
[1] JAESIN LEE. Identification of N-ethyl-α-ethylphenethylamine in crystalline powder seized for suspected drug trafficking: a research chemical or a new designer drug[J]. Forensic Toxicology, 2012, 31 1: 54-58. DOI:
10.1007/s11419-012-0158-1[2] PIETER A. COHEN Bastiaan J V John C Travis. A methamphetamine analog (N,α-diethyl-phenylethylamine) identified in a mainstream dietary supplement[J]. Drug Testing and Analysis, 2013, 6 7-8: 805-807. DOI:
10.1002/dta.1578[3] ROBERT OBERLENDER David E N. Structural variation and (+)-amphetamine-like discriminative stimulus properties[J]. Pharmacology Biochemistry and Behavior, 1991, 38 3: Pages 581-586. DOI:
10.1016/0091-3057(91)90017-v
