Uses
4-Trifluoromethoxybenzyl Bromide is a useful synthetic intermediate. It is used to prepare (nitro)[(trifluoromethoxy)benzyloxy]dihydroimidazo[2,1-b][1,3]oxazines with antitubercular activities. It is also used to synthesize tetrahydronaphthalenols with anti-allergic activities.
Chemical Properties
Colorless to light yellow liqui
Uses
4-(Trifluoromethoxy)benzyl bromide may be used in the synthesis of bioreductive drug, (6
S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5
H-imidazo[2,1-
b][1,3]oxazine (PA-824).
General Description
Polymerizations of 4-(trifluoromethoxy)benzyl bromide, via Friedel-Crafts polymerization using aluminum chloride as a catalyst has been reported.
