N-Boc-PEG4-bromide
- Product NameN-Boc-PEG4-bromide
- CAS1392499-32-9
- CBNumberCB03373736
- MFC15H30BrNO6
- MW400.31
- MDL NumberMFCD31536756
- MOL File1392499-32-9.mol
Chemical Properties
| Boiling point | 459.3±40.0 °C(Predicted) |
| Density | 1.223±0.06 g/cm3(Predicted) |
| solubility | Soluble in DCM |
| pka | 12.23±0.46(Predicted) |
N-Boc-PEG4-bromide Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| BroadPharm BP-23789 | 250mg | $540 | N-Boc-PEG4-bromide 98% |
Buy |
| Activate Scientific AS103627 | 1g | $665 | BocNH-PEG4-CH2CH2Br 95+% |
Buy |
| AK Scientific 0954EB | 1g | $856 | N-Boc-PEG5-bromide |
Buy |
| Crysdot CD64000172 | 1g | $600 | N-BOc-peg4-bromide 95% |
Buy |
| Acrotein AC-8220 | 0.25g | $220 | BocNH-PEG4-CH2CH2Br 97% |
Buy |
N-Boc-PEG4-bromide Chemical Properties,Usage,Production
Description
N-Boc-PEG4-bromide is a PEG linker containing a bromide group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.Biological Activity
N-Boc-PEG5-bromide is a PROTAC linker that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).in vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| Cleavable
| PEGs
| Alkyl/ether
|
Preparation Products And Raw materials
N-Boc-PEG4-bromide Suppliers
Global(50)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 | |
| +86-021-61551413 +8618813727289 |
contact@trustwe.com | China | 5738 | 58 | |
| +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 | |
| 027-65563561 18717150066 |
3207347307@qq.com | CHINA | 1238 | 58 | |
| +862156762820 +86-13564624040 |
sales@myuchem.com | China | 6710 | 58 | |
| 571-86758373 +8613588754946 |
sales@huarongpharm.com | CHINA | 3149 | 58 | |
| +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 | |
| +undefined18143011203 | info@chemextension.com | China | 42057 | 58 | |
| +86-15680926068 +86-15680926068 |
1924344760@confluore.cn | China | 2893 | 58 | |
| +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
View Lastest Price from N-Boc-PEG4-bromide manufacturers
1392499-32-9, N-Boc-PEG4-bromideRelated Search
- 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol
- t-Boc-N-amido-PEG5-acid
- O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL)
- N-Boc-PEG5-alcohol
- Biotin-PEG36-PFP ester
1of4
PROMPT×
PROMPT
The What'sApp is temporarily not supported in mainland China
The What'sApp is temporarily not supported in mainland China
Cancel
Determine