tebufloquin

Uses

Tebufloquin is a fungicide used in the preparation of new quinoline derivatives against Pyricularia oryae and Erysiphe cichoracearum.

Production Methods

The commercial production of tebufloquin involves the synthesis of a substituted quinoline core, specifically 6-tert-butyl-8-fluoro-2,3-dimethylquinolin-4-yl acetate. The process includes electrophilic substitution, fluorination, and acetylation steps, followed by purification to yield a high-purity crystalline powder.

Definition

ChEBI: Tebufloquin is a member of the class of quinolines that is quinoline which is substituted at positions 2 and 3 by methyl groups and at positions 4, 6, and 8 by acetoxy, tert-butyl, and fluorine, respectively. A fungicide developed mainly for the control of rice blast (Magnaporthe grisea), it has also been found to be effective against fungal diseases in soya beans and tomatoes. It has a role as an antifungal agrochemical. It is a member of quinolines, an organofluorine compound and an acetate ester.

Mechanism of action

Protective and curative. Inhibits mitochondrial electron transport processes and so disrupts energy production

Pesticide Type

Fungicide