Description
BODIPY 630/650X succinimide ester (SE) is an amine-reactive fluorescent probe that contains an integrated aminohexanoyl linker (X). It displays excitation/emission maxima of 630/650 nm, respectively. BODIPY 630/650X SE has been used, linked to adenosine A
1 receptor ligands, as a fluorescent probe to quantify ligand-receptor binding using fluorescence correlation spectroscopy.
Uses
BDY 630-X, SE, can be used as Fluorescent reagent for the labeling of amines.
Definition
ChEBI: BODIPY 630/650-X is a pyrrolidinone and a BODIPY dye. It has a role as a fluorochrome. It is functionally related to a 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene.
References
[1] S J BRIDDON. Quantitative analysis of the formation and diffusion of A1-adenosine receptor-antagonist complexes in single living cells.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 13: 4673-4678. DOI:
10.1073/pnas.0400420101[2] CLARE L. DALE B K S Hill. New potent, short-linker BODIPY-630/650 labelled fluorescent adenosine receptor agonists[J]. MedChemComm, 2012, 3 1: 333-338. DOI:
10.1039/c2md00247g
