Uses
ZD-1611 is a potent, orally active, selective ETA receptor antagonist, used for the research of ischemic stroke.
References
[1] Wilson C, et al. Pharmacological profile of ZD1611, a novel, orally active endothelin ETA receptor antagonist. J Pharmacol Exp Ther. 1999 Sep;290(3):1085-91. PMID:10454481
[2] Stenman E, et al. Cooperative effect of angiotensin AT(1) and endothelin ET(A) receptor antagonism limits the brain damage after ischemic stroke in rat. Eur J Pharmacol. 2007 Sep 10;570(1-3):142-8. Epub 2007 Jun 9. DOI:
10.1016/j.ejphar.2007.05.049
