Dolutegravir D3

Uses

Isotope labelled Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Uses

Dolutegravir D3 is intended for use as an internal standard for the quantification of Dolutegravir by GC- or LC-mass spectrometry.