(R)-Gyramide A Hydrochloride

Uses

(R)-Gyramide A is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 μM. It does not affect the closely related enzyme topoisomerase IV. (R)-Gyramide A demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs range from 10-80 μM).[Cayman Chemical]

Uses

(R)-Gyramide A Hydrochloride is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity. It does not affect the closely related enzyme topoisomerase IV.