Description
Biotin-PEG7-amine is a biotin PEG reagent that is reactive with NHS ester or with carboxutlic acid in the presence of EDC or HATU activator.
Uses
Biotin-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
reaction suitability
reaction type: Biotinylations
reagent type: cross-linking reagent
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:
10.1016/j.ebiom.2018.09.005