Description
17-
phenyl trinor Prostaglandin D
2 (17-
phenyl trinor PGD
2) is a novel, chemically stable analog of PGD
2 wherein the lower side chain is modified by the addition of a phenyl group at C-
17 in place of the last 3 ω-
chain carbon atoms. This modification has not been reported in a D-
type prostaglandin. However, in the PGE and PGF series, the analogous modification leads to a stable, somewhat more potent agonist which embodies the same biological activities as the parent prostaglandins.
Uses
17-phenyl trinor Prostaglandin D2 (17-phenyl trinor PGD2) is a novel, chemically stable analog of PGD2 wherein the lower side chain is modified by the addition of a phenyl group at C-17 in place of the last 3 ω-chain carbon atoms. This modification has not been reported in a D-type prostaglandin. However, in the PGE and PGF series, the analogous modification leads to a stable, somewhat more potent agonist which embodies the same biological activities as the parent prostaglandins.[Cayman Chemical]
Definition
ChEBI: A prostanoid that is 18,19,20-trinor-prostaglandin D2 in which one of the terminal methyl hydrogens has been replaced by a phenyl group.
![(Z)-7-[(1R)-5α-Hydroxy-2β-[(E,S)-3-hydroxy-5-phenyl-1-pentenyl]-3-oxocyclopentan-1α-yl]-5-heptenoic acid Structure](https://www.chemicalbook.com/CAS/20180808/GIF/85280-91-7.gif)
