Anti-RAB21, member RAS oncogene family

Uses

Anti-Rab21 (C-terminal) antibody produced in rabbit may be used in:

• immunoblotting
• immunoprecipitation
• immunofluorescence

Biological Activity

Ras-related protein Rab-21 (Rab21) and Rab5 are integrin-associated proteins, acting as positive regulators of integrin traffic. The association of Rab21 with integrins modulates cell adhesion and migration. It is also involved in endosome morphology and function. Rab21 is associated with squamous carcinoma and its expression is elevated in glioma.