ANTI-OREXIN RECEPTOR 1

Biological Activity

Orexin is a neuropeptide th at modulates the energy and metabolism balance. The effects of orexin are mediated by one of the two G protein-coupled receptors, orexin receptor 1 or 2. OXRs are expressed in oxinergic projection areas of the brain and regulate food intake by reducing systemic and brain signals th at drive over-eating.