Uses
β-Estradiol 6-(
O-carboxy-methyl)oxime: BSA has been used:
- to test its effect on the N-methyl-D-aspartate receptor (NMDAR) currents in female dorsal root ganglion (DRG) neurons
- to coat microplates for the detection of plasma 17β-Estradiol levels using indirect enzyme-linked immunosorbent assay (ELISA)
- to test its effect on MutL homolog 1 in colorectal cancer lines
General Description
β-Estradiol 6-(
O-carboxy-methyl)oxime: BSA is an estradiol conjugate and is membrane-impermeable. BSA is linked to the estradiol at position 6 to form the β-estradiol 6-(
O-carboxymethyl) oxime: BSA conjugate.
Biochem/physiol Actions
β-Estradiol 6-(O-carboxy-methyl)oxime: BSA mimics estrogen and favors amyloid precursor protein α (sAPPα) secretion in vitro studies with primary rat cortical neurons. It also stimulates mitogen-activated protein kinase (MAPK) activity in human umbilical vein endothelial cells
