(4-Methoxy-pyridin-2-yl)-methanol

Synthesis

Using 4-methoxy-2-methylpyridine as a raw material, 4-methoxy-2-methylpyridine-1-oxide was obtained by oxidation with m-chloroperoxybenzoic acid (m-CPBA). The 4-methoxy-2-methylpyridine-1-oxide was then hydrolyzed with trifluoroacetic anhydride to obtain 4-methoxy-2-hydroxymethylpyridine trifluoroacetate, which was then freed to obtain the target compound (4-methoxypyridin-2-yl)methanol [1]. The synthesis reaction formula of (4-methoxypyridin-2-yl)methanol is shown in the figure below:

Figure 1 Synthesis reaction formula of (4-methoxypyridin-2-yl)methanol

Application

(4-Methoxypyridin-2-yl)methanol is a useful research chemical for organic synthesis and other chemical processes.