Description
3-Phenylpropanoyl-coenzyme A (3-phenylpropanoyl-CoA) is a derivative of CoA (Item Nos. 16147 | 21499 | 21722) that contains the medium-chain and phenyl-substituted fatty acid 3-phenylpropanoic acid.1 It has been used as an enzymatic substrate in potential screening assays for medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting, in newborn-derived primary fibroblasts.WARNING This product is not for human or veterinary use.
References
[1] T G J DERKS. Neonatal screening for medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in The Netherlands: the importance of enzyme analysis to ascertain true MCAD deficiency.[J]. Journal of Inherited Metabolic Disease, 2008, 31 1: 88-96. DOI:
10.1007/s10545-007-0492-3
