Biological Activity
Thymidine kinase 1 (TK1) takes part in the process of DNA synthesis. It catalyzes the formation of pyrimidine deoxynucleotides through salvage pathway. The enzyme is an ATP dependent kinase. TK1 serves as a biomarker, indicating the recurrence of tumor and metastasis of cancer including gastrointestinal cancer, leukemia and lymphoma.
