(+)-N-(o-Chlorbenzyl)-α-methylphenethylaminhydrochlorid

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

• Sicherheit

  P264：Nach Gebrauch gründlich waschen.

  P264：Nach Gebrauch gründlich waschen.

  P270：Bei Gebrauch nicht essen, trinken oder rauchen.

  P301+P312：BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

  P330：Mund ausspülen.

  P501：Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  White Solid

• Originator

  Asenlix,Aventis

• Verwenden

  The S-enantiomer of Clobenzorex (C583000), an anorexic.

• Manufacturing Process

  A solution of 21.0 g (0.15 mol) of 2-chlorobenzaldehyde in 100 ml of ethanol (95%) was added to a solution of 20.5 g (0.152 mol) of D-1-phenyl-2-aminopropane in 100 ml of ethanol (95%). After standing for 15 h at room temperature, the ethanol was driven off, and the oily residue was then distilled to yield 36.2 g (94%) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane, boiling point 142°-146°C/0.1 mm Hg.
  To the solution of 36.0 g (0.14 mol) of D-N-(2-chlorobenzylidene)-2-amino-1- phenylpropane in 200 ml of dry methanol were added, in portions, 5.3 g (0.14 mol) of sodium borohydride. The mixture was stirred for 1 h at room
  temperature, and refluxed for 1 h water (100 ml) was then added and the methanol was removed in vacuo. After acidifying carefully with dilute hydrochloric acid, the solution was made alkaline by dilute sodium hydroxide, and extracted with ether. 33.0 g (90%) of D-N-(1-phenyl-2-propyl)-2-
  chlorobenzylamine, boiling point 132°-134°C/0.1 mm Hg, were obtained by distillation.

• Therapeutic Function

  Anorexic

(+)-N-(o-chlorobenzyl)-alpha-methylphenethylamine hydrochloride Upstream-Materialien And Downstream Produkte

(+)-N-(o-Chlorbenzyl)-α-methylphenethylaminhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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