Prochazon

proquazone Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Anti-inflammatory.

• Verwenden

  Proquazone is a non-steroidal anti-inflammatory drug.

• Definition

  ChEBI: Proquazone is a member of pyrimidines.

• Trademarks

  Arthrex (Novartis), Biarison (Swiss-Pharma, Egypt; Biochemie, Austria; ICN Alkaloida, Hungary; Sandoz, Finland, Turkey).

• Clinical Use

  Proquazone has been used successfully to treat rheumatoid polyarthritis. At 900 mg/d it is comparable in effect to 150 mg/d of indomethacin. Gastrointestinal disturbances are the principal adverse effects observed with its use.

• Synthese

  Synthesis: proquazone is prepared by the alkylation of 2-amino-4-methylbenzophenone with 2-iodopropane in the presence of sodium carbonate to give 4-methyl-2-[(1- methylethyl)amino]benzophenone, which is condensed with urethane in the presence of zinc chloride at 190 ?C.
  

Prochazon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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