2’-O-Methyl-rA(N-Bz)phosphoramidite

2’-O-Methyl-rA(N-Bz)phosphoramidite Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  White or off-white power

• Verwenden

  (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a nucleotide used in the synthesis of native-like crosslinked duplex RNA.

• Allgemeine Beschreibung

  Proligo′s 2′O-Methyl RNA monomers are compatible with fast deprotectionschemes that are based on the application of aliphatic amines, such asmethylamine. The adenosine and guanosine monomers are protected bythe standard benzoyl (bz) and isobutyryl (ib) groups.2′O-Methyl RNA is a nucleic acid analog that is characterized by theexceptional hybridization properties that it imparts with complimentary DNA or RNA, as well as increased stability against enzymatic degradationcompared to natural nucleic acids.The unique combination of properties of 2′O-Methyl RNA had foundwidespread use in the fields of:
  Diagnostic probes
  Aptamer and ribozyme development
  Mixed 2′O-Methyl-RNA/DNA antisense molecules

2’-O-Methyl-rA(N-Bz)phosphoramidite Upstream-Materialien And Downstream Produkte

2’-O-Methyl-rA(N-Bz)phosphoramidite Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(176)Suppliers