QUERCETINPENTAACETATE

QUERCETINPENTAACETATE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Pentaacetylquercetin is a pentaacetylated derivative of the flavonoid quercetin that has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in vitro (IC₅₀ = 3.74 μg/ml) and inhibits iron(II) chloride-induced lipid peroxidation in rat liver mitochondria (IC₅₀ = 20.2 μg/ml). Pentaacetylquercetin inhibits LPS-induced increases in nitrite (IC₅₀ = 8.7 μM) and PGE₂ production, as well as inducible nitric oxide synthase (iNOS) and COX-2 levels, in RAW 264.7 cells when used at concentrations of 20 and 40 μM. It also inhibits the growth of HL-60, U937, and SK-MEL-1 cells (IC₅₀s = 38, 25, and 58 μM, respectively).

• Verwenden

  [5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

QUERCETINPENTAACETATE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(22)Suppliers

1064-06-8, QUERCETINPENTAACETATE Verwandte Suche: