indicine-N-oxide

indicine-N-oxide Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Heliotropiurn indicurn also contains this base which has the structure given above based upon comparison with the preceding alkaloid. The base has proved to be highly active against transplanted neoplasts, Walker-256 carcinosarcoma, melanoma B-16, leukaemia L-12l 0, leukaemia P-388 and leukaemia P-1534 in mice and rats, giving up to 91 per cent inhibition of transplanted growth at a daily dosage of 200 mgm. per kilo.

• Verwenden

  Indicine N-oxide is a pyrrolizidine alkaloid that is isolated from Heliotropium indicum, one of the most widely used herbs in India. Indicine N-oxide exhibits antitumour and antimitotic activity in humans, and has subsequently undergone Phase I & II trials in adults and children with leukemia and solid tumours.

• Einzelnachweise

  Rao, McBride., U.S. Patent, 3,717,710 February 20,1973

indicine-N-oxide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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