2,2'-Ethylenedianiline Struktur

2,2'-Ethylendianilin

Bezeichnung:2,2'-Ethylendianilin

CAS-Nr34124-14-6

Englisch Name:2,2'-Ethylenedianiline

CBNumberCB9107940

SummenformelC14H16N2

Molgewicht212.29

MOL-Datei34124-14-6.mol

Synonyma

2,2'-Ethylendianilin

2,2'-Ethylendianilin physikalisch-chemischer Eigenschaften

Schmelzpunkt	72-77 °C
Siedepunkt	342.14°C (rough estimate)
Dichte	1.0799 (rough estimate)
Brechungsindex	1.6000 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit	Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand	Solid
pka	4.49±0.10(Predicted)
Farbe	Pale Yellow to Beige
InChI	InChI=1S/C14H16N2/c15-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)16/h1-8H,9-10,15-16H2
InChIKey	ZYHQGITXIJDDKC-UHFFFAOYSA-N
SMILES	C(C1=CC=CC=C1N)CC1=CC=CC=C1N
LogP	1.929 (est)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	20/21/22
S-Sätze:	36/37

Gefahreninformationscode (GHS)

2,2'-Ethylenedianiline Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Chemische Eigenschaften
BROWN POWDER
Verwenden
2,2''-Ethylenedianiline is used as a reagent to synthesize Oxcarbazepine (O869250), a broad-specturm, second-generation anticonvulsant drug that is used to treat partial and complex partial seizures in children and adults. 2,2''-Ethylenedianiline is also used as a reagent to prepare a series of triterpines (e.g. Lupeol [L474850]), compounds that have chemopreventative activity.
Synthese

612-23-7

34124-14-6

A. Preparation of loaded nickel catalysts In a 25 mL round-bottomed flask, 4.75 g of nickel chloride hexahydrate was dissolved in 15 mL of deionized water, 20 g of neutral alumina was added, sonicated and dried overnight. Weigh 0.3 g of sodium borohydride and prepare 800 mL of 0.01 mol/L solution. Add 5 g of precursor to a 1 L flask, add mechanical stirring, and slowly add aqueous sodium borohydride solution, filter the product after the reaction is complete and dry to obtain the desired catalyst. B. Synthesis of 2,2'-(ethane-1,2-diyl)diphenylamine In a 10 mL round bottom flask, 300 mg of 2-nitrobenzyl chloride, 300 mg of catalyst, 2 mL of deionized water and 2 mL of 60% hydrazine hydrate were slowly added dropwise with magnetic stirring until complete incorporation and stirred continuously for 20 min at room temperature to obtain the reaction mixture. The reaction mixture was extracted with ethyl acetate and analyzed by GC-MS to give about 51% yield of the target product. The catalyst was washed three times each with water and ethanol and dried for reuse.
Einzelnachweise
[1] Patent: CN107417542, 2017, A. Location in patent: Paragraph 0014-0015; 0016-0017

2,2'-Ethylenedianiline Upstream-Materialien And Downstream Produkte

2,2'-Ethylendianilin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

34124-14-6, 2,2'-Ethylenedianiline Verwandte Suche:

Send Inquriy