Medrylamin

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

medrylamine Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Medrylamine,Shanghai Lansheng Corporation

• Definition

  ChEBI: Medrylamine is a diarylmethane.

• Manufacturing Process

  A 116 parts by weight of phenyl-p-methoxy-chloromethane (4- methoxybenzhydryl chloride) were added to 500 parts by weight of toluene and to the resulting mixture 65 parts by weight of 2-dimethylaminoethanol was added. Then the entire mixture was refluxed for two hours. The refluxed mixture was cooled and 250 parts by weight of a 10% solution of sodium hydroxide were added. This alkaline mixture was then steam distilled until the distillate was only weakly alkaline, for example a pH 7.5-8.
  The residue of this steam distillation was then mixed with 200 parts by weight of benzene and washed with water until the wash waters were practically neutral. The benzene solution was then evaporated to dryness until the resulting mixture was of constant weight (145 parts). This product was oily and was then dissolved in 3000 parts by weight of dry ether; and treated while being agitated with the theoretically equivalent amount of dry hydrochloric acid dissolved in ether. This product is an oily product, which solidified after standing overnight in an ice box. The ether solution was decanted off and the solidified residue was dissolved in 1500 parts by weight of dioxane, and then precipitated with 3000 parts by weight of ether while being continuously agitated. The resulting solid product was the hydrochloride of 2-(p-methoxy-α-phenylbenzyloxy)-N,N-dimethylethylamine 100 parts by weight of the desired product were obtained corresponding to a yield of 62% and having a melting point of 141°C.

• Therapeutic Function

  Antihistaminic

medrylamine Upstream-Materialien And Downstream Produkte

Medrylamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(7)Suppliers

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