Y 134

Y 134 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Y 134 is a SERM displaying selectivity for ERα over ERβ.

• Definition

  ChEBI: [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(4-propan-2-yl-1-piperazinyl)phenyl]methanone is an aromatic ketone.

• Biologische Aktivität

  Selective estrogen receptor modulator (SERM) that displays selectivity for ER α over ER β (K i values are 0.09 and 11.31 nM respectively) and no cross-reactivity with mineralocorticoid, glucocorticoid, androgen and progesterone receptors. Acts as an agonist in the bone and antagonist in reproductive tissue. Suppresses estrogen-stimulated proliferation of ER-positive human breast cancer MCF-7 and T47D cells.

• Lager

  Desiccate at RT

Y 134 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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