Indan-5-ol

Bezeichnung:Indan-5-ol

CAS-Nr1470-94-6

Englisch Name:5-INDANOL

CBNumberCB8210012

SummenformelC9H10O

Molgewicht134.18

MOL-Datei1470-94-6.mol

Synonyma

Indan-5-ol

Indan-5-ol physikalisch-chemischer Eigenschaften

Schmelzpunkt	51-53 °C (lit.)
Siedepunkt	255 °C (lit.)
Dichte	0.8540 (rough estimate)
Brechungsindex	1.5630 (estimate)
Flammpunkt	>230 °F
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	6.3g/l
Aggregatzustand	powder to crystal
pka	10.37±0.20(Predicted)
Farbe	slightly brown
BRN	1936314
CAS Datenbank	1470-94-6(CAS DataBase Reference)
EPA chemische Informationen	5-Indanol (1470-94-6)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	21-20/21/22
S-Sätze:	36/37-36
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS-Nr.	NK7525000
Hazard Note	Irritant
HazardClass	6.1
PackingGroup	III
HS Code	29062900

Gefahreninformationscode (GHS)

5-INDANOL Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R21:Gesundheitsschädlich bei Berührung mit der Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
5-Indanol, mp 54–55 ℃, bp 255 ℃, is produced from indan [496-11-7] by a sulfonation–alkali-fusion process. A synthesis for 1,1,3,3-tetraalkylindanols was developed by Bayer, which involves the reaction of isoolefins with secondary alkenylphenols (or compounds generating them under the reaction conditions) at 100–250 ℃ and in the presence of acidic catalysts. An example is the reaction of isobutene with bisphenol A in the presence of acid-activated clays which yields 1,1,3,3-tetramethyl-5-indanol [53718-26-6], mp 115 ℃, bp (2.66 kPa) 156 ℃, in a yield of 80% of the theoretical, and 4-tert-butylphenol as a coproduct.
Chemische Eigenschaften
light brown to grey-brown crystalline powder or
Verwenden
5-Indanol is a 5-hydroxyindole analog with weak inhibitory activity against human melanoma tyrosinase. 5-Indanol is also used as a reagent in the preparation of Sodium Indanylcarbinicillin (S635000); a compound which has been shown to reduce blood pressure in mammals and also has been used as a b-lactam antibiotic.
Definition
ChEBI: A member of the class of phenols that is indan which has been hydroxylated at position 5.
läuterung methode
Crystallise 5-hydroxyindane from pet ether (m 56o) or pentane (m 59-60o). It has UV with max at 283.5nm (cyclohexane). The 3,5-dinitrobenzoyl derivative has m 156o. [Beilstein 6 III 2428, 6 IV 3829.]

5-INDANOL Upstream-Materialien And Downstream Produkte

Indan-5-ol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1470-94-6, 5-INDANOL Verwandte Suche:

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