Calcitriol-d6

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Achtung

• Gefahrenhinweise

  H225：Flüssigkeit und Dampf leicht entzündbar.

  H319：Verursacht schwere Augenreizung.

• Sicherheit

  P210：Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Calcitriol-d6 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Calcitriol-d6 is intended for us as an internal standard for the quantification of calcitriol by GC- or LC-MS. Calcitriol is synthesized from 7-dehydro cholesterol in humans via a non-enzymatic photochemical reaction with 290-310 nm UV light in the skin. Hydroxylation of the resulting cholecalciferol in the liver produces 25-hydroxy vitamin D₃, the principal circulating form of vitamin D. A second, tightly regulated hydroxylation in the kidney produces calcitriol. Plasma calcitriol levels range from 10-70 pg/ml and are influenced by numerous dietary and hormonal factors. The main physiologic effects of calcitriol are to increase the absorption of calcium at the level of the intestinal epithelium, and to increase the mineralization of bone via the direct stimulation of osteoblasts.

• Chemische Eigenschaften

  Off-White to Pale Yellow Solid

• Verwenden

  The biologically active form of vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic

• Verwenden

  1α,25-Dihydroxyvitamin D3-26,26,26,27,27,27-d₆?can be used as an analytical standard for the quantitative analysis of dihydroxyvitamin D3?concentration in human serum via LC-MS.

• Allgemeine Beschreibung

  1α,25-Dihydroxyvitamin D3?[1,25(OH)₂D₃], also known as calcitriol, plays a role in calcium and phosphate metabolism in humans. It also regulates insulin secretion and induces cellular differentiation.
  1α,25-Dihydroxyvitamin D3-26,26,26,27,27,27-d₆?is a deuterated vitamin D3 wherein C-26 and C-27 carbon methyl protons are replaced by deuterium.

Calcitriol-d6 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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