Bifemelane HCl

Bifemelane HCl Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Bifemelane is a nootropic reported to have antianoxic, anti-ischemic and memory enhancing activities. In man, bifemelane appears to increase cerebral blood flow, while in rodents it reverses scopolamine-induced dementia. Bifemelane has an added adrenergic component reportedly arising from norepinephrine uptake inhibition.

• Originator

  Mitsubishi; Eisai (Japan)

• Verwenden

  Bifemelane Hydrochloride, is an antidepressant MAO inhibitor. It has also been reported to protect neural tissues against ischemic damage and age-related neurodegeneration.

• Manufacturing Process

  N-Methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine was prepared from 2- (5-bromopentyloxy)diphenylmethane and of methylamine in ethanol is at 50°C in a sealed tube (heating for 3 hours). Ethanol and excess methylamine are distilled in vacuo, 2 N NaOH aqueous solution is added, and the reaction product is extracted with ether. Dry hydrogen chloride gas is passed into the ether solution, and the precipitate collected by filtration. Recrystallization from ethanol-ether gives N-methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine hydrochloride, m.p. 87.5-89.5°C.

• Trademarks

  Alnert; Celeport

• Therapeutic Function

  Antidepressant, Antiulcer, Nootropic

• Hazard

  Moderately toxic by ingestion.

• Lager

  Desiccate at RT

Bifemelane HCl Upstream-Materialien And Downstream Produkte

Bifemelane HCl Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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