(R)-(+)-1,2-Dithiolane-3-pentanoic acid

Bezeichnung:(R)-(+)-1,2-Dithiolane-3-pentanoic acid

CAS-Nr1200-22-2

Englisch Name:(R)-(+)-1,2-Dithiolane-3-pentanoic acid

CBNumberCB7765979

SummenformelC8H14O2S2

Molgewicht206.33

MOL-Datei1200-22-2.mol

(R)-(+)-1,2-Dithiolane-3-pentanoic acid physikalisch-chemischer Eigenschaften

Schmelzpunkt	48-52 °C(lit.)
alpha	D23 +104° (c = 0.88 in benzene)
Siedepunkt	185-195 °C(Press: 0.5 Torr)
Dichte	1.218±0.06 g/cm3(Predicted)
Brechungsindex	114 ° (C=1, EtOH)
Flammpunkt	>230 °F
storage temp.	-20°C
Löslichkeit	Acetonitrile (Slightly), Chloroform (Slightly), DMSO
Aggregatzustand	Solid
pka	5.4(at 25℃)
Farbe	Light Yellow to Yellow
Optische Aktivität	[α]20/D +104°, c = 1 in chloroform
Merck	14,9326
LogP	2.160 (est)
CAS Datenbank	1200-22-2(CAS DataBase Reference)

Sicherheit

R-Sätze:	22-36/38
S-Sätze:	20-36-26-35
WGK Germany	3
HS Code	29349990

Gefahreninformationscode (GHS)

(R)-(+)-1,2-Dithiolane-3-pentanoic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
Yellow Crystalline Solid
Verwenden
α-Lipoic acid has been used as a reference standard for the analysis of α-lipoic acid in human plasma by high performance liquid chromatography coupled to electron capture detector (HPLC-ECD), in various food matrices and dietary supplements by HPLC combined with coulometric electrode array detector (CEAD) as well as electrospray ionization mass spectrometer (ESI-MS).
It may be used as a reference standard for the determination of α-lipoic acid in human urine by isocratic reversed-phase HPLC and in α-lipoic acid capsules by HPLC with chemiluminescence detection.
Verwenden
A fat-metabolism stimulator
Definition
ChEBI: (R)-lipoic acid is the (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties. It has a role as a prosthetic group, a nutraceutical and a cofactor. It is a lipoic acid, a member of dithiolanes, a heterocyclic fatty acid and a thia fatty acid. It is functionally related to an octanoic acid. It is a conjugate acid of a (R)-lipoate. It is an enantiomer of a (S)-lipoic acid.
Allgemeine Beschreibung
α-Lipoic acid is an antioxidant which is generally present in plants, animals and many other microorganisms.
Biochem/physiol Actions
(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease.

(R)-(+)-1,2-Dithiolane-3-pentanoic acid Upstream-Materialien And Downstream Produkte

(R)-(+)-1,2-Dithiolane-3-pentanoic acid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1200-22-2, (R)-(+)-1,2-Dithiolane-3-pentanoic acid Verwandte Suche:

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