ALPHA-NAPHTHYL PHOSPHATE DISODIUM SALT Struktur

Dinatriumnaphthylphosphat

Bezeichnung:Dinatriumnaphthylphosphat

CAS-Nr2183-17-7

Englisch Name:ALPHA-NAPHTHYL PHOSPHATE DISODIUM SALT

CBNumberCB7720907

SummenformelC10H10NaO4P

Molgewicht248.15

MOL-Datei2183-17-7.mol

Synonyma

Dinatriumnaphthylphosphat

Dinatriumnaphthylphosphat physikalisch-chemischer Eigenschaften

Schmelzpunkt	>300°C
storage temp.	-20°C
BRN	4895811
CAS Datenbank	2183-17-7(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
WGK Germany	3
F	10-21

Gefahreninformationscode (GHS)

ALPHA-NAPHTHYL PHOSPHATE DISODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Verwenden
1-Naphthyl phosphate disodium salt has been used:
- as a component in the mixture for soaking the chromatography paper for determining acid phosphatase activity
- in the staining of the alkaline phosphatase isoforms in 7.5% non-denaturing polyacrylamide gel
- as a component in the mixture for soaking the chromatography paper for preparing acid phosphomonoesterase-reactive imprinting sheets
- as a component in the staining solution for staining the roots for determining phosphomonoesterase activity
läuterung methode
Purify the salt through an acid ion-exchange column (in H+ form) to give the free acid [1136-89-6], M 224.2, which is obtained by freeze drying and recrystallising from Me2CO/*C6H6, or by adding 2.5volumes of hot CHCl3 (or 20 parts of boiling *C6H6) to a hot solution of 1 part acid and 1.2 parts Me2CO and cooling (m 155-157o, 157-158o). The acid is dissolved in the minimum volume of H2O to which 2 equivalents of NaOH are added and then freeze dried, or by adding the equivalent amount of MeONa in MeOH to a solution of the acid in MeOH and collecting the Na salt, washing with cold MeOH, then Et2O, and drying in a vacuum. [Friedman & Seligman J Am Chem Soc 72 624 1950, Chanley & Feageson J Am Chem Soc 77 4002 1955.] The monosodium salt [1136-89-6] is similarly prepared but by using 1 equivalent of NaOH. The phosphate group is hydrolysed at pH 1.1-5.85 at 70o. [Beilstein 6 IV 4226.] It is a substrate for alkaline phosphatase [Gomori Methods Enzymol 4 381 1957, 128 212 1968], and prostatic phosphatase [Babson Clin Chem 30 1418 1984]. [See p 538 in “Metal-organic Compounds”, Chapter 5, Beilstein 6 IV 4226.]

Dinatriumnaphthylphosphat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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