Abacavir 5’-Phosphate

Abacavir 5’-Phosphate Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  White Solid

• Verwenden

  Abacavir 5’-Phosphate (Abacavir - In House Impurity) is a metabolite of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

• Definition

  ChEBI: Abacavir monophosphate is the organic phosphate that is the 5'-monophosphate of abacavir. It has a role as a metabolite. It is a member of 2,6-diaminopurines and an organic phosphate. It is functionally related to an abacavir.

Abacavir 5’-Phosphate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(20)Suppliers

136470-77-4, Abacavir 5’-Phosphate Verwandte Suche: