[1aR-(1aα,7α,7aβ,7bα)]-1a,2,3,5,6,7,7a,7b-Octahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulen

Bezeichnung:[1aR-(1aα,7α,7aβ,7bα)]-1a,2,3,5,6,7,7a,7b-Octahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulen

CAS-Nr21747-46-6

Englisch Name:(+)-Ledene

CBNumberCB7153554

SummenformelC15H24

Molgewicht204.35

MOL-Datei21747-46-6.mol

Synonyma

[1aR-(1aα,7α,7aβ,7bα)]-1a,2,3,5,6,7,7a,7b-Octahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulen

[1aR-(1aα,7α,7aβ,7bα)]-1a,2,3,5,6,7,7a,7b-Octahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulen physikalisch-chemischer Eigenschaften

Schmelzpunkt	269°C
Siedepunkt	268-270 °C (lit.)
Dichte	0.927 g/mL at 20 °C (lit.)
Brechungsindex	n20/D 1.504
storage temp.	Refrigerator
Löslichkeit	Chloroform (Sparingly), Ethanol (Slightly)
Aggregatzustand	Oil
Farbe	Colourless
Optische Aktivität	[α]20/D +68±2°, c = 10% in ethanol
BRN	2554786
LogP	6.447 (est)

Sicherheit

S-Sätze:	23-24/25
WGK Germany	3

(+)-Ledene Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
(+)-Ledene, also called leden or viridiflorene, is an organic compound that belongs to the group of 5, 10-cycloaromadendrane sesquiterpenoids. These compounds are derived from the aromadendrane skeleton through a cyclization reaction between carbon atoms 5 and 10. (+)-Ledene is mainly found in saliva and is considered to have low solubility in water and a relatively neutral nature. In cellular environments, (+)-ledene is predominantly present in the cell membrane (predicted based on logP) and cytoplasm.
Verwenden
(+)-Ledene is an essential oil that is synthesized by viridiflorene synthase. It has been studied as an antioxidant, antimicrobial, antibiofilm and to treat various cancers.
Definition
ChEBI: Viridiflorene is a carbotricyclic sesquiterpene obtained from several natural sources, including Australian Tea Tree oil (Melaleuca alternifolia.) It is a sesquiterpene and a carbotricyclic compound.
Allgemeine Beschreibung
(+)-Ledene is a naturally occurring sesquiterpene that can be prepared from (+)-aromadendrene via isomerization.
Einzelnachweise
[1] DUC N. TRAN Prof.??Dr. N C. Biomimetic Synthesis of (+)-Ledene, (+)-Viridiflorol, (?)-Palustrol, (+)-Spathulenol, and Psiguadial A, C, and D via the Platform Terpene (+)-Bicyclogermacrene[J]. Chemistry - A European Journal, 2014. DOI:10.1002/chem.201403082.
[2] S. L. GWALTNEY K. J S S T Sakata. Bridged to Fused Ring Interchange. Methodology for the Construction of Fused Cycloheptanes and Cyclooctanes. Total Syntheses of Ledol, Ledene, and Compressanolide[J]. The Journal of Organic Chemistry, 1996. DOI:10.1021/jo961005a.

[1aR-(1aα,7α,7aβ,7bα)]-1a,2,3,5,6,7,7a,7b-Octahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulen Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

21747-46-6, (+)-Ledene Verwandte Suche:

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