MMP-9 INHIBITOR I

MMP-9 INHIBITOR I Chemische Eigenschaften,Einsatz,Produktion Methoden

• Definition

  ChEBI: MMP9 inhibitor I is a hydroxamic acid that is N-hydroxy-3-methylbenzamide in which the the hydrogens at positions 2 and 5 have been replaced by benzyl[(4-methoxyphenyl)sulfonyl]amino and (diethylamino)methyl groups, respectively. It is a cell-permeable, potent, selective, and reversible inhibitor of matrix metallopeptidase-9 (MMP-9, EC 3.4.24.35). It has a role as an EC 3.4.24.35 (gelatinase B) inhibitor. It is a hydroxamic acid, a tertiary amino compound, a sulfonamide and an aromatic ether.

• Allgemeine Beschreibung

  A cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC₅₀ = 5 nM). Also inhibits MMP-1 (IC₅₀ = 1.05 μM) and MMP-13 IC₅₀ = 113 nM) at higher concentrations.

• Biochem/physiol Actions

  Primary TargetMMP-9

MMP-9 INHIBITOR I Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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