12-Oxo-5-α-spirostan-3-β-ylacetat

HECOGENIN ACETATE Chemische Eigenschaften,Einsatz,Produktion Methoden

• S-Sätze Betriebsanweisung:

  S22:Staub nicht einatmen.
  S24/25:Berührung mit den Augen und der Haut vermeiden.

• Beschreibung

  Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin that has anthelmintic and antinociceptive properties. It reduces the percentage of mobile larvae in goat fecal cultures containing Haemonchus, Oesophagostomum, and Trichostrongylus nematodes (EC₅₀ = 0.49 mg/ml). Hecogenin acetate (5, 10, or 20 mg/kg, i.p.) inhibits development of mechanical hyperalgesia induced by carrageenan, TNF-α, dopamine , and prostaglandin E₂ (PGE₂; ) in mice. It also increases latency to tail withdrawal in the tail flick test and has no effect on motor performance in the rotarod test in mice when administered at a dose of 40 mg/kg.

• Verwenden

  Hecogenin Acetate, is a derivative of Hecogenin (H129945), which is a sapogenin present in the leaves of species from the Agave genus, possessing wide spectrum of pharmacology activities, such as having antinociceptive properties.

• Definition

  ChEBI: HECOGENIN ACETATE is a triterpenoid.

• läuterung methode

  Crystallise the acetate from MeOH. [Beilstein 19 IV 2583.]

12-Oxo-5-α-spirostan-3-β-ylacetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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