Heterophyllin B

Heterophyllin B Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  White crystal, easily soluble in methanol, derived from Radix Radix.

• Verwenden

  Taizishencyclopeptide B has the functions of invigorating qi and blood, invigorating body fluid and invigorating the spleen and stomach. And it was used for content determination/identification/pharmacological experiments, etc.

• Biologische Aktivität

  Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla. It can be used in esophageal cancer research.

• in vitro

  Heterophyllin B (0-200 μM; 12-48 hours) reduces cell viability in the 75, 100 and 200 μM groups, has no effect on 5, 10, 25 and 50 μM groups.Heterophyllin B (0 -50 μM; 6 hours) suppresses the expression levels of p-PI3K, p-AKT and β-catenin in a dose-dependent manner in ECA-109 cells.

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  Cell Viability Assay

  Cell Line:	ECA-109 cells
  Concentration:	5 μM, 10 μM, 25 μM, 50 μM, 75 μM, 100 μM and 200 μM
  Incubation Time:	12, 24 and 48 hours
  Result:	Decrease cell viability at high concentrations.

  Western Blot Analysis

  Cell Line:	ECA-109 cells
  Concentration:	0 μM, 10 μM, 25 μM, 50 μM
  Incubation Time:	6 hours
  Result:	Decreased the phosphorylation of PI3K/AKT and the expression of β-catenin.

Heterophyllin B Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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