DL-2-Amino-4-(ethylthio)buttersaeure

Bezeichnung:DL-2-Amino-4-(ethylthio)buttersaeure

CAS-Nr67-21-0

Englisch Name:DL-ETHIONINE

CBNumberCB6165509

SummenformelC6H13NO2S

Molgewicht163.24

MOL-Datei67-21-0.mol

Synonyma

DL-2-Amino-4-(ethylthio)buttersaeure

DL-2-Amino-4-(ethylthio)buttersaeure physikalisch-chemischer Eigenschaften

Schmelzpunkt	265-268 °C
alpha	[α]D20 0±0.5° (c=5, dil. HCl)
Siedepunkt	310℃
Dichte	1.164
Brechungsindex	1.5500 (estimate)
Flammpunkt	142℃
storage temp.	-20°C
Löslichkeit	Methanol (Slightly, Heated), Water (Slightly)
pka	2.23±0.10(Predicted)
Aggregatzustand	Crystalline Powder or Flakes
Farbe	White to off-white
Wasserlöslichkeit	Soluble in water.
Merck	14,3738
BRN	1722529
CAS Datenbank	67-21-0(CAS DataBase Reference)
EPA chemische Informationen	S-Ethylhomocysteine (67-21-0)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26
WGK Germany	3
RTECS-Nr.	ES6825200
TSCA	Yes
HS Code	29309090
Toxizität	The Sethyl analog of methionine. It is a carcinogen and hepatotoxic agent once proposed as an antineoplastic agent. It inhibits the incorporation of methionine and glycine into proteins and substitutes for methionine in transmethylation reactions, the ethyl group appearing in the products in place of the methyl groups of methionine (e.g., ethylcholine is formed instead of choline). Ethionine is currently used only as an experimental compound in studies of hepatotoxicity and methionine metabolism and nutrition.

Gefahreninformationscode (GHS)

DL-ETHIONINE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
Off-White Solid
Verwenden
antineoplastic; inhibitor DNA methylation
Verwenden
DL-Ethionine is used as a dietary supplement to accelerate cholangiocarcinogenesis in vivo. It is also used to induce oxidative stress in liver to study the levels and activities of anti-oxidative enzymes and compounds such as glutathione.
Definition
ChEBI: A non-proteinogenic alpha-amino acid that is methionine in which the S-methyl group is replaced by an S-ethyl group.
Allgemeine Beschreibung
White crystalline flakes.
Air & Water Reaktionen
Slightly soluble in water.
Reaktivität anzeigen
A synthetic thio-substituted amino acid.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition DL-ETHIONINE emits toxic fumes of NOx and SOx.
Brandgefahr
Flash point data for DL-ETHIONINE are not available; however, DL-ETHIONINE is probably combustible.
Biochem/physiol Actions
DL-Ethionine is a racemic mixture of the anti-methylation agent L-Ethionine and its enantiomer D-Ethionine. DL-Ethionine is used as a dietary supplement to accelerate cholangiocarcinogenesis in vivo. DL-Ethionine is used to induce oxidative stress in liver to study the levels and activities of anti-oxidative enzymes and compounds such as glutathione.
Sicherheitsprofil
Mddly toxic by ingestion and intraperitoneal routes. Suspected carcinogen with experimental carcinogenic and tumorigenic data. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.

DL-ETHIONINE Upstream-Materialien And Downstream Produkte

DL-2-Amino-4-(ethylthio)buttersaeure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

67-21-0, DL-ETHIONINE Verwandte Suche:

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