Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate is an ester derivative, mainly used as a pharmaceutical intermediate.

• Synthese

  The synthesis method of Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate is as follows: Dissolve 10 g (0.066 mol) of m-nitrobenzaldehyde and 11 g (0.067 mol) of ethyl chloroacetate in 60 ml of benzene, and add 1 ml of piperidine. 1 ml of glacial acetic acid, heated in a water bath, and the water generated in the reaction was continuously removed with a Dean-start water separator. After refluxing for 3h, the benzene was evaporated, 20ml of ether was added to the residue, frozen, crystallized, suction filtered, and dried to give 16.2g of methyl 2-hydroxypyridine-4-carboxylate, yield 82%, mp 92 -96°C.

Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate Upstream-Materialien And Downstream Produkte

Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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