Medibazin

medibazine Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Vialibran,Servier

• Verwenden

  Medibazine is studied as a distinguishing compound with antibacterial activity by artificial neural networks.

• Definition

  ChEBI: Medibazine is a diarylmethane.

• Manufacturing Process

  To a solution of 32 g piperonyl piperazine in 100 ml anhydrous toluene, 10 g sodium carbonate are added and 35.2 g benzhydryl chloride are added dropwise. The mixture is then heated to reflux for 7 hours with vigorous agitation. Then the mixture is cooled, the salt that has formed is filtered out and 100 ml water is added. The organic layer is extracted with several batches of 10% methane sulfonic acid. The acid extracts are combined and washed with ether then alkalized with sodium carbonate. The mixture is extracted with several batches of chloroform and the combined chloroform solutions are washed several times with water. After drying and solvent evaporation, the crude base of 1-diphenylmethyl-4-piperonyl-piperazineis isolated and the hydrochloride thereof is formed in acetone. After recrystallization 22.5 g of the dihydrochloride are finally obtained. M.P.: 228°C, from methanol.

• Therapeutic Function

  Coronary vasodilator

medibazine Upstream-Materialien And Downstream Produkte

Medibazin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(5)Suppliers

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